What do you call a difficult problem in chemistry?

A chemystery.

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Chemistry Jokes More Chemistry Jokes

Why will I go down in history?

I dunno, but I'll go down in math and chemistry too.

Why don't people tell Chemistry jokes?

Because they never get a reaction.

Difficult Problem Jokes More Difficult Problem Jokes

What do mathematicians say when they encounter a difficult problem?

f(x)

What do you call a difficult problem in chemistry?

A chemystery.